However, some causes, such as swollen lymph nodes and direct injury, may only affect one side of the throat. Having just one side of your throat hurt may be due to a minor infection or injury, but it can also be a serious problem, so know when to see a provider. A sore throat may cause general pain, or you may only feel it on one side Experiencing a sore throat on only one side can be concerning, but it is not always a sign of something serious A sore throat is a common symptom of various conditions, but some causes, such as swollen lymph nodes and direct injury, may only affect one side of the throat. This unilateral throat pain feels distinctly different from the typical sore throat that accompanies a cold or flu, which usually affects the entire throat area uniformly
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