The aging process is accompanied by a continuous decline of the cardiac system, disrupting the homeostatic regulation of cells, organs, and systems Aging increases the prevalence of cardiovascular diseases, thus heart failure and mortality. As plaque accumulates on the arterial walls, it reduces their flexibility and narrows the space within the arteries. Cardiac ageing manifests as a decline in function leading to heart failure At the cellular level, ageing entails decreased replicative capacity and dysregulation of cellular processes in. In summary, the pathophysiology of severe heart failure weaves together various interlinked conditions like ischemic heart disease, hypertension, and valvular heart disease, each playing a pivotal role in the decline of cardiac function.
When assessing and treating an injured patient of this age, you must recall that His ability to physiologically compensate for his injury might be impaired due to an inability to increase cardiac output. As we age, multiple processes likely contribute to cardiac dysfunction, including fibrosis, inflammation, mechanical stiffening and diastolic dysfunction, mitochondrial dysfunction, and a growing imbalance between loss and birth of cardiomyocytes (center).
OPEN
