Like other antidepressants that affect serotonin, trintellix has been associated with low sex drive and difficulty achieving orgasm. Sexual side effects are common with antidepressants in both men and women, but there are options to prevent or reduce such side effects. A study found that trintellix (vortioxetine) improved sexual function in patients with major depressive disorder who switched from other antidepressants The study compared trintellix with escitalopram and showed that trintellix had better scores on a sexual function assessment questionnaire. Learn about common side effects of trintellix including sexual side effects See full safety info, including boxed warning for suicidal thoughts & actions & med guide.
Vortioxetine (trintellix, formerly called brintellix) What to do if you experience sexual side effects from ssris about 35% to 50% of people with untreated major depression experience some type of sexual dysfunction prior to treatment So in some cases, sexual difficulties may stem not from the ssri, but rather from the underlying depression. Key takeaways as an antidepressant, trintellix can cause negative sexual side effects like lower libido and difficulty with arousal or orgasm Trintellix is a serotonin modulator, which means it works like an ssri but has an added mechanism of action that may reduce its overall effects on sex drive In studies and clinical trials, trintellix has been shown to have fewer side effects than.