Because hemophilia genes are passed down on the x chromosome, males with hemophilia are much more likely to have serious bleeding symptoms than females. The genes associated with these conditions are located on the x chromosome, which is one of the two sex chromosomes In males (who have only one x chromosome), one altered copy of the gene in each cell is sufficient to cause the condition. This genetic basis explains its distinct inheritance pattern and why certain groups are more affected Information about how haemophilia is inherited in males and females, with genetic inheritance diagrams In some cases of haemophilia, there is no known family history
This may be because the alteration to the haemophilia gene is new, known as a spontaneous mutation, or that no affected males have been known in the family. Hemophilia inheritance in the most common types of hemophilia, the faulty gene is located on the x chromosome Everyone has two sex chromosomes, one from each parent Females inherit an x chromosome from the mother and an x chromosome from the father Males inherit an x chromosome from the mother and a y chromosome from the father.
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